Metabolic and gut microbial characterization of obesity-prone mice under high-fat diet （文献分享一组-赵容丽)

【Metabolic and gut microbial characterization of obesity-prone mice under high-fat diet （文献分享一组-赵容丽)】的更多相关文章

Metabolic and gut microbial characterization of obesity-prone mice under high-fat diet （文献分享一组-赵容丽)

题目:高脂饮食下易肥胖小鼠的代谢和肠道微生物特性研究 Metabolic and gut microbial characterization of obesity-prone mice under high-fat diet 期刊:Journal of Proteome Research 发表时间:February 22, 2019 DOI:10.1021/acs.jproteome.8b00945 分享人:赵容丽内容与观点: 肥胖在世界范围内广泛流行,是代谢疾病的关键危险因素,常可引发糖脂…

解读人：闫克强，Metabolic and gut microbial characterization of obesity-prone mice under high-fat diet（高脂饮食下易胖倾向小鼠的代谢和肠道微生物菌群特征分析）

单位: 上海中医药大学蚌埠医学院上海交通大学附属第六人民医院夏威夷大学癌症中心第二军医大学技术:非靶向代谢组学,16S rRNA测序技术一. 概述: 本研究对小鼠进行高脂饮食,根据体重增长率将其分为易胖类小鼠(OP)和不易胖小鼠(OR).通过气相质谱对其血浆代谢物进行分析,同时利用16S rRNA测序的方法对其肠道微生物进行测序分析.在Con,OP,OR共鉴定到60种差异代谢物,其中27种是OP相关的.这些差异代谢物重要集中于糖酵解.脂质和氨基酸代谢.TCA循环等.在肠道研究中,OP…

Metabolic Signatures of Cystic Fibrosis Identified in Dried Blood Spots For Newborn Screening Without Carrier Identification (文献分享一组-孔楠楠)

题目:Metabolic Signatures of Cystic Fibrosis Identified in Dried Blood Spots For Newborn Screening Without Carrier Identification(新生儿筛查(不含携带者鉴定)中使用干血片鉴定囊性纤维化的代谢特征) 期刊:Journal of Proteome Research 发表时间:December 3, 2018 DOI:10.1021/acs.jproteome.8b00351…

Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation (文献分享一组-黄旭蕾)

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肠道微生物研究进展 | Microbiology | Human Gut Microbiome | human gut microbiota

之前我有过一篇16s基本概念和数据分析的文章.16S 基础知识.分析工具和分析流程详解可以分成两部分,生物层面和技术层面. 生物层面: 1. 肠道微生物里面包含了哪些微生物?显然包含了所有层面的微生物:细菌.古细菌和真菌. 2. 肠道微生物是如何从母体遗传向下一代的?成熟的肠道微生物群体是如何逐步形成的?环境因素占比多少? 3. 肠道微生物是通过什么来影响疾病的? 4. 目前常见的肠道微生物层面的治疗方案有哪些?疗效如何?哪些病是纯粹由肠道微生物引起的? 技术层面: 1. 什么是16s测序.宏…

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