Today, I'll share a review papers about Epigenetic Landscape, the Epigenetic Landscape is related to cell differentiation. It comes from Current Biology, published in 2012. Bistability, Bifurcations, and Waddington’s Epigenetic Landscape [1] This pap…

I'll share another review paper about Epigenetic Landscape, it comes from Nature Review, published in 2016. Transition states and cell fate decisions in epigenetic landscapes [1] In this paper, they suggest that there might be a fundamental flaw in t…

CVPR 2016 Visual Tracking Paper Review  本文摘自:http://blog.csdn.net/ben_ben_niao/article/details/52072659    http://blog.csdn.net/ben_ben_niao/article/details/52078727 做了一段时间的跟踪,最近CVPR大会也过了一段时间了,这次将CVPR2016跟踪的文章做一次总结,主要是对paper的方法,创新,改进等方面进行介绍和总结.具体的实现细…

How to transform the day time images to night time ?  A series of paper review and some thinkings about this point.  Unsupervised Holistic Image Generation from Key Local Patches  2017-07-20   14:34:27  无监督的进行基于关键局部 patch 的图像生成,这个算是和 “传统”的 GAN 稍微不同的地…

急性髓系白血病 ( acute myeloid leukemia, AML ) 是成年人常见的血液系统恶性肿瘤之一,主要表现为髓系原始细胞克隆性恶性增殖及正常造血细胞功能抑制.在AML基因突变图谱中,fms样酪氨酸激酶3 ( fms-like receptor tyrosine kinase 3, FLT3 ) 基因突变最为常见,存在于约1/3初诊AML患者.FLT3突变形式主要包括跨膜区内部的串联重复突变 ( ITD ) 和累及活化环中的点突变( TKD ) 两种形式.虽然这些突变影响细胞功能…

------------------------------- Long noncoding RNAs are rarely translated in two human cell lines. (蛋白,多肽) Bánfai B, Jia H, Khatun J, Wood E, Risk B, Gundling WE Jr, Kundaje A, Gunawardena HP, Yu Y, Xie L, Krajewski K, Strahl BD, Chen X, Bickel P, Gi…

sklearn实战-乳腺癌细胞数据挖掘(博客主亲自录制视频教程) https://study.163.com/course/introduction.htm?courseId=1005269003&utm_campaign=commission&utm_source=cp-400000000398149&utm_medium=share https://en.wikipedia.org/wiki/Omnibus_test Omnibus tests are a kind of st…

基因调控网络的概念在之前已经简要介绍过:https://www.cnblogs.com/pear-linzhu/p/12313951.html 沃丁顿表观遗传景观(The Waddington's epigenetic landscape) 是描述基因调控下细胞分化的动态性的一个经典的隐喻,是由沃丁顿在1957年提出的.他将细胞分化比喻作从高处沿山坡滚落下的小球,直到一个稳定的盆地 (basin),该盆地也就代表一定的分化状态.小球最开始能量较高,处于不稳定状态,对应干细胞等未分化的细胞状态,小…

[怪毛匠子-整理] awesome-single-cell List of software packages (and the people developing these methods) for single-cell data analysis, including RNA-seq, ATAC-seq, etc. Contributions welcome... Software packages RNA-seq anchor - [Python] - ⚓ Find bimodal,…

TCGA的关键数字:图片来源<细胞> 由美国政府发起的癌症和肿瘤基因图谱(Cancer Genome Atlas,TCGA)计划于2006年联合启动,目前已经收录了来自1万多例病人的33种癌症的数据,2.5PB的数据量.全世界无数顶尖肿瘤学家经过10多年的辛苦工作,于近期公布了TCGA研究的收官之作:“Pan-Cancer Atlas”泛癌症图谱.这些研究精华共发表了27篇相关论文,涉及基因组测序,转录组测序,甲基化等表观组学测序以及最终的整合分析,同时研究者也将它们与临床和影像数据相关联,展…