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AD(Alzheimer’s disease):不可逆的神经退化,患病人员会由于脑部问题的恶化而导致心智功能不健全. ADNI:阿尔茨海默氏症神经成像项目 ADNI的总体目标是验证用于阿尔茨海默病临床治疗试验的生物标记物 Study Design 该研究支持关于减慢和停止AD的恶化进程的治疗方案的发展和研究.最终目标是确证在老年痴呆症的临床治疗中使用的生物指标(生物标记物) 通过研究来自多种形式的ADNI剖面的和纵向的数据已经得到的知识: AD病理在人们外表正常且没有记忆丢失的时候就已经出现,而…
相关名词: MCI:轻度认知功能障碍 EMCI:早期认知障碍 MCI:轻度认知障碍 LMCI:晚期认知障碍 CN:认知正常的志愿者 DTI:doppler tissue imaging,多普勒组织显像,是一种描述大脑结构的新方法,是核磁共振成像(MRI)的特殊形式. 一.认识ADNI 1.ADNI主要用于早期发现与追踪阿尔茨海默病,同时提供一个平台,方便全球人员之间能够共享数据. 2.ADNI研究的总体目标: (1)在尽可能早的阶段(痴呆前)检测AD,并确定用生物标志物跟踪疾病进展的方法. (2…
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