0. 基本参数 基因组大小:G Read读长:L 总Read条数:n_r 1. 碱基深度分布 单条Read测序覆盖到某一个碱基的概率:L/G 因为L/G很小,n_r很大,每个碱基覆盖深度服从泊松分布. 则每个碱基的覆盖深度的期望为:d_n=(L/G)*n_r 2. K-mer深度分布 假设基因组对K是unique的,可以得到G个不同的K-mer. 单条Read测序覆盖某个K-mer的概率:(L-K+1)/G 同样因为(L-K+1)/G很小,n_r很大,每个K-mer的覆盖深度服从泊松分布. 则每

http://www.geekwire.com/2012/chart-pays-seattle-software-engineers/ Chart: Who pays the most in Seattle for software engineers BY JOHN COOK on February 2, 2012 at 3:14 pm     15 Comments Share  35 Tweet Share  19 Reddit Email FAQ: What to know for to

CentOS / Redhat : Configure CentOS as a Software Router with two interfaces   Linux can be easily configured to share an internet connection using iptables. All you need to have is, two network interface cards as follows: a) Your internal (LAN) netwo

Windows应用软件 Windows Applications (TBU) 全本推荐微软Windows 10操作系统 Quanben recommends Microsoft Windows 10 开发工具 Development Tools 软件名称Name of Application 版本认证Version 说明Description 适用平台System 评级Rating 官网或安全资源链接Offcial/Download Link Git for Windows 当前版本Curren

原文作者:kkun 原文地址:http://www.cnblogs.com/kkun/archive/2011/07/06/agile_software_development.html 敏捷是什么 敏捷开发是一种软件开发方法,基于迭代和增量开发,通过自组织,跨团队,沟通协作完成开发工作. 敏捷宣言的诞生 2001年2月11日到13日,17位软件开发领域的领军人物聚集在美国犹他州的滑雪胜地雪鸟(SnowBird)雪场.经过两天的讨论,“敏捷”(Agile)这个词为全体聚会者所接受,用以概括一套全

First we should know some basic conceptions about network: 1.Every PC is supposed to have its own IP,So we can connent other's PC by WAN.That's just like a ID of netwrok world.   2.But if  every PC has its own IP,Then IPs of this world will be insuff

Atitit GRASP(General Responsibility Assignment Software Patterns),中文名称为"通用职责分配软件模式" 1. GRASP (职责分配原则)1 1.1. GRASP设计模式 1 1.2. 9个基本的OO设计原则或基本的设计构件.这9个设计模式分别是:创建者(Creator).信息专家(Information Expert).低耦合(Low Coupling).控制器(Controller).高内聚(High Cohesion

用Java客户端程序访问Java Web服务器时出错: java.net.SocketException: Software caused connection abort: socket write error at java.net.SocketOutputStream.socketWrite0(Native Method) at java.net.SocketOutputStream.socketWrite(Unknown Source) at java.net.SocketOutputS

最近在整一台华硕笔记本,大概有5年寿命了吧,质量还行,由于系统出了问题,打算用自制U盘WinPE进去修复一下.按照个人经验,在主板设置里启用了USB启动选项,并且设置USB启动顺序为第一个,可是进系统居然报错,如下图所示. Windows failed to start. A Recent hardware or software change might be the cause. To fix the problem: 1. Insert your windows installation

软件开发流程(Software development process)即软件设计思路和方法的一般过程,包括设计软件的功能和实现的算法和方法.软件的总体结构设计和模块设计.编程和调试.程序联调和测试以及编写.提交程序.1需求调研分析 ●相关系统分析员和用户初步了解需求,然后用WORD列出要开发的系统的大功能模块,每个大功能模块有哪些小功能模块,对于有些需求比较明确相关的界面时,在这一步里面可以初步定义好少量的界面. ●系统分析员深入了解和分析需求,根据自己的经验和需求用WORD或相关的工具再做出

COMPUTER ORGANIZATION AND ARCHITECTURE DESIGNING FOR PERFORMANCE NINTH EDITION Software cache coherence schemes attempt to avoid the need for additional hard-ware circuitry and logic by relying on the compiler and operating system to deal with the pr

关于Ubuntu 汉化时的错误解决:按照网上的方法没有解决 最后 删掉thunderbird mail .这个软件,顺利解决!! 错误:thunderbird-locale-en: Depends: thunderbird (>= 1:24.4.0+build1-0ubuntu1) ubuntu software database is broken错误该怎么解决?安装Ubuntu之后默认英文,选简体中文,正常来说这样装好就应该能用的,可是这个时候又出现了错误broken package dat

When I was studying Philosophy at Berkeley, a friend told me that she could tell who was going to be rich and who was not. Fascinating, I thought. But when I asked how, she refused to answer and only said that I would figure it out. So after 20 years

Blender Blender is the best free and open source 3D modelling program out there by a long shot! The program is under constant development, has a huge community and has been used in many major films for video editing and 3D concepts. As Said before bl

http://www.agner.org/optimize/#manuals 阅读笔记Optimizing software in C++   7. The efficiency of different C++ constructs 栈的速度快是因为,总是反复访问同一段地址,如果没有大的数组,肯定实在L1 cahce中. 全局静态区,global,static变量,float constants, string constants, array initializer lists,switch

recourse: "Software Engineering", Ian Sommerville Keywords for this chapter: planning scheduling cost estimation Project planning takes place at three stages in a project life cycle: At the proposal stage (When you are bidding for a contract to

I've learned a lot in my software engineering class about how a program comes out.That's also a essential part from the whole procedure. Here I wanna share something in my mind with you. 一般说来,我们可以把软件的生命周期划分为软件定义.软件开发.软件运行三个时期. 软件定义时期是生命周期的第一个时期,也是软件开

Motivation 程序员是否需要在处理一致性问题或者同步时,一定要make hands dirty?能不能专注于应用级原子性,而无需考虑低层操作系统.运行时支持的原子性概念或者语言构造? 软件事务性内存(Software Transactional Memory, STM)提供了一种机制,极大的减少了业务型程序员在处理并发任务时所需投入的努力. Scope 这一领域相对而言比较新但不是很新,尤其对具有关系型或得关系型数据库领域知识背景的人来说. 本文不对该概念起源和研究趋势做任何阐述和探究,

VS2010打开.csproj工程文件报错,不能加载,错误信息如下: 无法计算HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\MSBuild\ToolsVersions\14.0@VCTargetPath处的属性表达式 这一般是由于安装了Vs2015和VS2010冲突产生的我问题,即使卸载了VS2015也无济于事. 解决办法: 打开windows+R输入regedit,进入注册表找到:HKEY_LOCAL_MACHINE\SOFTWARE\Wow6432Node\Mi

Every great piece of software begins with customer's big idea. As a professional softeware developer, it's your job bring the idea into life, turning it into working code that satisfies your customers. Deliver software that's needed, on time & on bud

Junit和Hamcrest的安装需要先把两个jar文件下载到本地,具体取得方式多种多样,我是直接从同学那要的.新建一个java项目,在新建时直接在库中导入这两个包即可. 这次编程内容是一个测试三角形类型的小程序,具体代码在GitHub上已详细给出,这里主要是对测试进行讨论.有四种类型,分别为not a triangle, equilateral, isosceles and scalene. 我输入了如下八项进行测试: public static Collection prepareData(