目录 1.conda安装 2.配置RepBase 3.RepeatMasker避坑 4.RepeatProteinMask避坑 5.RepeatModeler避坑 6.自定义重复序列库 后记 1.conda安装 conda安装虽然简单,但还是有很多坑,而且很多都是隐形的坑. # conda install -c bioconda repeatmasker conda install -c bioconda repeatmodeler repeatmodeler依赖于repeatmasker,因此

RM是library-based,通过相似性比对来识别重复序列,可以屏蔽序列中转座子重复序列和低复杂度序列(默认将其替换成N).使用数据库Dfam和Repbase. The Dfam database is a collection of Repetitive DNA element sequence alignments, hidden Markov models (HMMs) and matches lists for complete Eukaryote genomes. Repbase是

最近天气变化无常,身为程序猿的寡人!~终究难耐天气的挑战,病倒了,果然,程序猿还需多保养自己的身体,有句话这么说:一生只有两件事能报复你:不够努力的辜负和过度消耗身体的后患.话不多说,开始吧. 一.什么是简单工厂模式 简单工厂 (Simple Factory)又称静态工厂方法模式(Static Factory Method Pattern) 使用的频率也是非常高,它的官方解释为:定义一个用于创建对象的接口,让子类决定实例化哪一个类.工厂模式使一个类的实例化延迟到其子类. 这个模式本身很简单而且使

原文链接:http://www.c-sharpcorner.com/UploadFile/19b1bd/design-patterns-simplified-part3-factory/ Design Patterns Simplified - Part 3 (Simple Factory)[设计模式简述--第三部分(简单工厂)] This article explains why and how to use the Simple Factory Design Pattern in softw

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A Simple Tree Problem Time Limit: 3 Seconds      Memory Limit: 65536 KB Given a rooted tree, each node has a boolean (0 or 1) labeled on it. Initially, all the labels are 0. We define this kind of operation: given a subtree, negate all its labels. An

工厂模式简介. 工厂模式专门负责将大量有共同接口的类实例化 工厂模式可以动态决定将哪一个类实例化,不必事先知道每次要实例化哪一个类. 工厂模式有三种形态: 1.简单工厂模式Simple Factory,又称静态工厂方法模式 2.工厂方法模式Factory Method,又称多态性工厂模式 3.抽象工厂模式Abstract Factory,又称工具箱模式 2.什么是简单工厂模式 简单工厂模式是类的创建模式.是由一个工厂对象决定创建出哪一种产品类的实例,是不同的工厂方法模式的一个特殊实现.由一个工厂

A Simple Nim Problem Description   Two players take turns picking candies from n heaps,the player who picks the last one will win the game.On each turn they can pick any number of candies which come from the same heap(picking no candy is not allowed)

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A Simple OpenGL Shader Example II eryar@163.com Abstract. The OpenGL Shading Language syntax comes from the C family of programming languages. Tokes, identifiers, semicolons, nesting with curly braces, control-flow, and many key words look like C. GL

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以前看过一篇文章,具体内容不记得了,只记得它的结论了:懒是人类进步的源动力.当时觉得结论有点新颖,文中列举了大量的实例证明这个结论,其中重点强调了计算机学科.我本身从事算是计算机相关的工作,对文中的部分观点还是认可的. 特别是互联网时代,这个结论显得更加正确,而我则认为是make things simple是进步的动力,发明工具或者创新让事情简单起来,从而使更多人能够掌握以前不能做到的技能,进而推动世界的进步. 计算机行业不管是大数据,vr,机器学习还是什么,都是让人们更简单,而不是更复杂,作为

一.简单工厂模式简介(Bref Introduction) 简单工厂模式(Simple Factory Pattern)的优点是,工厂类中包含了必要的逻辑判断,根据客户端的选择条件动态实例化相关的类,对于客户端来说,去除了与具体产品的依赖 二.解决的问题(What To Solve) 客户实例化对象时不需要关心该对象是由哪个子类实例化的. 三.简单工厂模式分析(Analysis) 1.简单工厂模式结构 IProduct接口:抽象产品类 ConcreteProduct类:产品类的具体实现 Simp

30.9 Simple Network Management Protocol Network management protocols specify communication between the network management client program a manager invokes and a network management server program executing on a host or router. In addition to defining

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